(c) Enlarged AFM image of the framed region in (b), allowing the determination of the arrangement of αβ-tubulin dimers within the topographically lower PF, providing a high-resolution image of ...

XMAP215 functions as a processive polymerase... But how does XMAP215 promote the addition of so many tubulin dimers during its interaction with the microtubule end? Using negative-stain electron ...

(E) Microtubules consist of 13 protofilaments of tubulin dimers arranged in a hollow tube. (F) Neurofilaments have flexible polymer arms that repel neighboring neurofilaments and determine the ...

MTs are composed of α-tubulin and β-tubulin proteins, which polymerize into dimers and assemble into linear protofilaments that form a cylindrical lattice. Traditional methods like X-ray ...

[17] This pattern of effects on microtubule stabilization is distinct from that of other clinically important tubulin-targeting agents, which include taxanes, epothilones, and vinca alkaloids.