Food allergies can be life-threatening due to the rapid and exaggerated immune response. While mucosal mast cells (MMCs) are ...

Topical corticosteroids are still a mainstay of treatment for atopic dermatitis ... which then crosslinks preformed drug-specific IgE on mast cells, activating a cascade for allergic reaction.

Researchers from Shenzhen University have evaluated the potential antiallergic effects of the histone acetyltransferase KAT6A inhibitor WM-1119 on IgE-mediated mast cell activation and allergic ...

This inspired our research team to investigate the role of mucosal mast cells in the pathogenesis of food allergy." Initially, the researchers generated an IgE-mediated food allergy model using ...