The Black Death, the world’s most devastating plague outbreak, killed half of medieval Europe’s population in the space of seven years in the 14th century, shifting the course of human history.

The Black Death changed our immune systems — here’s how Survival of the fittest determined who lived through the plague. But those very genes may make us susceptible to other diseases.

Some, like those behind the bubonic plague, have had a big impact on our immune systems. The Black Death in the 14th century was the single deadliest event in recorded history, spreading ...

The Black Death which ravaged Europe 670 years ago may still be harming humans today a study found. Genetic mutations that helped humans survive the plague increased the risk of chronic diseases ...

The Black Death remains the single deadliest pandemic in recorded human history. The post Single gene evolution helped Black Death kill millions for centuries appeared first on Talker.

The Black Death, the world's most devastating plague outbreak, killed half of medieval Europe's population in the space of seven years in the 14th century, shifting the course of human history.

Before the Black Death, the variant of ERAP2 found to be protective of the plague was found in 40% of individuals included in the London study. After the Black Death, it was 50%.

The downside to the variant is that it has been linked to a greater susceptibility to autoimmune disorders, such as Crohn's disease, where the immune system becomes overactive. "This suggests that ...