Tertiary lymphoid structures (TLS) are increasingly recognized to have roles in cancer. Within tumor microenvironments (TME), TLS can arise as ectopic lymphoid organs containing aggregates of ...

This method could push the detection of protein function much further into the twilight zone of sequence identity. First, the tertiary structures of the sequences of interest are predicted either ...

Intrinsically disordered proteins (IDPs) do not attain a stable secondary or tertiary structure and ... by providing accurate ...

The intrinsically disordered proteins (IDPs) do not attain a stable secondary or tertiary structure and ... by providing accurate predictions of protein structures. We have now shown how to ...

tertiary structure, and often begins co-translationally. Protein folding requires chaperones and often involves stepwise establishment of regular secondary and supersecondary structures ...

Protein sequencing is a lot more challenging ... more complexity when working with 20 amino acids compared to four nucleotides, not to mention tertiary structures, folded domains, and so on. ClpX can ...

The three-dimensional shape of a protein determines its function. This is because proteins form attachments and interact with many other molecules and structures inside organisms. The shape of a ...

Proteins are composed of one or more chains of amino acids, which are linked together by peptide bonds and folded into specific three-dimensional structures ... sheets), tertiary (overall 3D shape), ...