A research team at Memorial Sloan Kettering Cancer Center (MSK) has made new insights into how the body forms immune cell clusters called tertiary lymphoid structures (TLSs) in response to foreign ...

To function correctly, cellular proteins depend not only on their complex tertiary and quaternary structures, but also on their proximity to and interactions with other molecules participating in ...

Advancements in artificial intelligence (AI) are dramatically transforming the field of protein science, offering powerful ...

The tertiary structure of proteins is such that it is suited to the function of the protein. Proteins function in different environments, and thus each protein has different requirements.

Read about new findings on how tertiary lymphoid structures form to fight foreign threats such as cancer.

Complex protein interactions at synapses are essential for memory formation in our brains, but the mechanisms behind these processes remain poorly understood. Now, researchers from Japan have ...

The intrinsically disordered proteins (IDPs) do not attain a stable secondary or tertiary structure and rapidly change their conformation, making structure prediction particularly challenging ...

The Journey to a Nobel Prize: A Protein Design and Structure Research Timeline About 50 years ago, biologists set out to solve the protein-folding problem. The road to the Nobel victory has been ...

Tertiary lymphoid structures (TLS) are ectopic cellular hubs that coordinate immunity within patient tumors. TLS also correlate with improved prognosis and superior response to immunotherapy. While ...

This kind of work has much more of a problem with finite training data than language models do - there are about 150,000 known protein structures, though a lot of them are very close homologues ...

Alphabet subsidiary DeepMind is releasing the structures of every protein known to science as identified by the AI AlphaFold. The AI transformed science and boosted research efforts across biology.