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However, in stem-cell lead research conducted by USC, Stem Cell scientists have revealed a new way to remove toxic tau proteins and lower Alzheimer's risks. The tau protein, which, when it becomes ...
A trio of studies published in the past year all suggest that the protein Reelin helps maintain thinking and memory in ailing brains, though precisely how it does this remains uncertain.
A new study has somewhat redeemed the tau protein, which up to now has been associated with the development of Alzheimer’s disease. Turns out, the protein has a ‘good guy’ role, helping to ...
It does the seeding, causing normal tau protein to misfold and join the fibrils." Using cryo-EM, the team examined the structure of the synthetic fibrils.
One dose of a new treatment, delivered by nasal spray, clears away build-ups of the toxic tau protein associated with Alzheimer’s disease from inside brain cells, improving memory, according to ...
This argues that mutations in Tau may reduce the protein's normal ability to prevent oxidative stress in addition to causing the protein to accumulate into the typical hallmarks of disease, as ...
The tau isoform 1N4R confers vulnerability of MAPT knockout human iPSC-derived neurons to amyloid beta and phosphorylated tau-induced neuronal dysfunction. Alzheimer's & Dementia, 2025 DOI: 10. ...
Preventing Tyr29 phosphorylation attenuates tau pathology, but TYK2 expression aggravates pathology in P301S mice. Credit: Nature Neuroscience (2024). DOI: 10.1038/s41593-024-01777-2 ...