Source Reference: Islam T, et al "Phospho-tau serine-262 and serine-356 as biomarkers of pre-tangle soluble tau assemblies in Alzheimer's disease" Nat Med 2025; DOI: 10.1038/s41591-024-03400-0.

A harmful form of the tau protein, which builds up in Alzheimer's disease and similar brain disorders, can directly damage blood vessels in the brain, according to a new study by researchers at ...

Key protein identified for understanding and treating Alzheimer's disease Date: March 2, 2025 Source: University of Cologne Summary: Researchers have identified a specific form of the tau protein ...

Feb 20, 2022 3:52 pm · Updated Feb 21, 2022 11:12 am ...

Phospho-tau serine-262 and serine-356 as biomarkers of pre-tangle soluble tau assemblies in Alzheimer’s disease. Nature Medicine. doi.org/10.1038/s41591-024-03400-0.

How to clear the toxic tau protein that can lead to Alzheimer's and related diseases Date: March 5, 2025 Source: Keck School of Medicine of USC Summary: The neurotransmitter glutamate is essential ...

Alzheimer’s protein found in newborns helps, not hurts By Paul McClure June 30, 2025 Newborns and people with Alzheimer's disease both have elevated levels of tau protein Depositphotos View 2 Images ...

Buchholz, S., et al. (2025) The tau isoform 1N4R confers vulnerability of MAPT knockout human iPSC-derived neurons to amyloid beta and phosphorylated tau-induced neuronal dysfunction.

Tau tangles typically form years after the formation of another protein called amyloid, which creates plaques in the brain and is one of the first hallmarks of Alzheimer’s. The greater the ...

The blood-based test could speed development of anti-tau treatments for Alzheimer’s, since drug developers can fairly quickly determine whether a compound they are testing is having any effect ...

The associations were in brain regions vulnerable to pre-clinical Alzheimer's disease, Coughlan noted. Tau was associated with a history of menopausal hormone therapy use in older but not younger ...