Systemic juvenile idiopathic arthritis (JIA) is the most severe subtype of JIA; treatment options are limited. Interleukin-6 plays a pathogenic role in systemic JIA. We randomly assigned 112 ...

Systemic juvenile idiopathic arthritis (sJIA) has long been recognized as unique among childhood arthritides, because of its distinctive clinical and epidemiological features, including an ...

Systemic Juvenile Idiopathic Arthritis Companies are Chugai Pharmaceutical, AstraZeneca, Pfizer, Incyte Corporation Novartis, Roche, Genentech, AbbVie, Pfizer, Eli Lilly and Company, Bristol Myers ...

It’s also called juvenile idiopathic arthritis, or JIA. It has several different types. Systemic-onset juvenile rheumatoid arthritis is the rarest form. The word "systemic" means that it affects ...

Treatment with open-label tofacitinib improved disease activity among patients with sJIA but did not significantly prolong the time to flare compared with placebo.

Interleukin-1 is pivotal in the pathogenesis of systemic juvenile idiopathic arthritis (JIA). We assessed the efficacy and safety of canakinumab, a selective, fully human, anti–interleukin-1β ...

Juvenile idiopathic arthritis is an autoimmune disorder ... Doctors may call this form “systemic.” Signs of this include joint swelling, fever, and a light pink rash. It may involve the ...

Your child has systemic juvenile idiopathic arthritis. Systemic JIA is one of the seven subtypes of arthritis that are included under the umbrella term of juvenile idiopathic — meaning having an ...

More information: Bruno Fautrel et al, EULAR/PReS recommendations for the diagnosis and management of Still's disease, comprising systemic juvenile idiopathic arthritis and adult-onset Still's ...

Juvenile idiopathic arthritis is arthritis in children 16 and under. The six subtypes of JIA are oligoarticular JIA, polyarticular JIA, psoriatic arthritis, enthesitis-related arthritis, systemic ...

Polyarticular JIA can affect both large and small joints, according to the Arthritis Foundation. Systemic juvenile idiopathic arthritis (SJIA) isn’t common: It affects about 10 to 15 percent of ...