Researchers have identified the mitochondrial calcium uniporter as a critical protein in the strengthening of synaptic ...

The characteristics of perforated synapses are consistent with this ... Is this a stable endpoint of synaptic plasticity, or are presynaptic release sites remodeled as well? Another important ...

They receive thousands of synaptic signals via their dendrites, with individual synapses undergoing activity-dependent plasticity. This synaptic plasticity is the mechanism underlying our memory ...

Virginia Tech neuroscientists have uncovered a mitochondrial process that helps brain cells adapt and strengthen connections, ...

Researchers have identified a unique mitochondrial process in CA2 neurons that supports learning, memory, and social ...

The physiological power and biological value of brain-derived neurotrophic factor is so significant that it is often referred ...

Given their importance in brain function, it is not surprising that improper synapse development and plasticity have been implicated in a wide range of neurodevelopmental, neuropsychiatric, and ...

but scientists continued to puzzle over how synaptic plasticity is maintained at individual synapses far from the nucleus. This puzzle intrigued Schuman, who is now the director of the Max Planck ...

So far, we have identified several novel features related to functions and regulation of AMPA and kainate-type glutamate receptors at the developing synapses. Our current research aims to understand ...

In particular, the existence of dendritic domains with distinct synaptic inputs, excitability, modulation and plasticity appears to be a common feature that allows synapses throughout the ...

Sleep's role to down-scale glutamate, excitatory, frontal cortical synapses is extended to include an up-scaling of metaplastic LTP potential, in recovery from prolonged waking induced saturation of ...