Here, we present evidence of a variant class of riboswitches that responds to adenine. These riboswitches carry an aptamer domain similar in sequence and secondary structure to the guanine aptamer ...

Adenine was first discovered in 1885 by the German physiologist Albrecht Kossel. He isolated adenine from the pancreas of oxen and named it "adenine" derived from the Greek word "aden," meaning gland.

The purine structure consists of a pyrimidine ring (positions 1 to 6) fused to an imidazole ring (positions 7 to 9). Adenine and guanine, the two most common purines in DNA and RNA, share this core ...

These “nucleobases” — adenine, guanine, cytosine, thymine and uracil — combine with sugars and phosphates to make up the genetic code of all life on Earth. Whether these basic ingredients ...

The work used recently developed techniques to identify not only adenine and guanine—which had previously been identified in samples from some of the same meteorites—but also cytosine, uracil, and ...

Urine levels of adenine, a metabolite produced in the kidney, are predictive and a causative biomarker of looming progressive kidney failure in patients with diabetes, a finding that could lead to ...