The substantia nigra is a motor nucleus located in the basal ganglia of the midbrain. This brain structure contributes to the body's cognitive and motor functions by sending signals to initiate or ...

This is required for the proper functioning of the basal ganglia system. The substantia nigra, which controls movement, is connected to the caudate nucleus and is also part of the basal ganglia.

13 May 2022 The death of dopaminergic neurons in the substantia nigra is the defining feature of Parkinson’s disease, but not all neurons in the region suffer this fate. Why do some wither while ...

For the first time, researchers have sorted large numbers of human brain cells in the substantia nigra into 10 distinct types. Just one is especially vulnerable in Parkinson’s disease, the team ...