Researchers reviewed cases in which patients experienced severe skin toxicities in response to immunotherapy, and sought to identify the distinct natures of these toxicities.

Of 48 Stevens-Johnson syndrome/toxic epidermal necrolysis cases, physicians identified a singular culprit drug for 17. Physicians identified 104 drugs as allergens for 48 patients.

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Retrospective analysis of Steven Johnson syndrome and toxic epidermal necrolysis over a period of 5 years from northern Karnataka, India. Indian Journal of Pharmacology , 45(1), 80–82. doi: 10. ...

Epidermal necrolysis (EN) — which includes Stevens-Johnson syndrome (SJS), toxic EN (TEN), and SJS and TEN overlap — had an incidence of 2.6 cases per million person-years in a French study of ...

The researchers used spatial proteomics to analyze skin samples from patients with toxic epidermal necrolysis. This cutting-edge approach, known as Deep Visual Proteomics, merges powerful ...

Toxic epidermal necrolysis is a rare but extremely severe adverse reaction to common medications, such as allopurinol (which is used to treat gout) or certain antibiotics. It causes widespread ...