biosynthesis inhibiting effect. Pathogenic variants in the DHCR7 gene result in SLOS with a hallmark sterol inhibition signature. This profile encompasses the accumulation of 7-DHC and 7-DHD and ...

They aimed to understand how proteins and lipids work together to create a functional ... likely due to sterols like ergosterol, the main sterol in yeast cells. Sterols modulate membrane fluidity ...

2014;9(4):417-427. Nevertheless, lipidomics is withstanding challenges in several aspects. First, lipids, which are the products of diet and removed from the inherited genome of organisms ...