Autotaxin (ATX) generates the lipid mediator lysophosphatidic ... the well-defined binding of the bile salt steroid moiety, agrees well with the structure–activity data, and prompted us to ...

Steroid biosynthesis ... some other groups of lipid transporters by their high degree of specificity. By mapping the aligned START domain sequences onto the crystal structure, we can now begin ...

LPD-3 was resolved as a 345-angstrom elongated tunnel-like structure with a hydrophobic interior filled by 27 lipid molecules and three additional phospholipids within its transmembrane domain.

A new framework bridges a gap in understanding RNA therapeutics by linking the structure of lipid nanoparticles to immune response. It can help scientists and engineers expand the use of RNA ...

Scientists have developed a method for analysing the structure of lipid nanoparticles that could be used to improve vaccine and drug delivery, targeting a wide range of health issues. A team led by ...

They were able to identify an insect steroid hormone that is crucial to both lipid metabolism and egg production in fruit flies. Their findings are published in Current Biology. Recent studies in ...

Scientists have developed a method for analysing the structure of lipid nanoparticles that could be used to improve vaccine and drug delivery, targeting a wide range of health issues. A team led ...

"The dogma in the steroid receptor field for 50 years has ... in the liver of transgenic and wild type mice suppresses all lipid synthesis. This includes cholesterol, triglycerides and fatty ...

Scientists have developed a method for analysing the structure of lipid nanoparticles that could be used to improve vaccine and drug delivery, targeting a wide range of health issues. (Nanowerk News) ...