More information: Alina Marymonchyk et al, Neural stem cell quiescence and activation dynamics are regulated by feedback input from their progeny under homeostatic and regenerative conditions ...

Discover how neural stem cells activate in the adult human brain, unlocking potential for regeneration, repair, and new ...

Scientists have discovered that neural stem cells (NSCs) receive constant feedback from their daughter cells, influencing whether they remain dormant or activate to form new neurons and glia.

This valuable work presents how PRDM16 plays a critical role during colloid plexus development, through regulating BMP signaling. Solid evidence supports the context-dependent gene regulatory ...

Another important aspect of quiescence is the phenotypic heterogeneity observed in yeast populations. Research has shown that during starvation, some cells enter a quiescent state while others ...

A University of Ottawa neuroscientist has led a Canadian research team to reveal important new insights into the activation dynamics of neural stem cells (NSCs). These are the stem cells that build ...

This image shows a postnatal neural stem cell (NSC) in the ventricular-subventricular ... are required for postnatal NSCs to acquire quiescence. A research group led by Kazunobu Sawamoto, a ...

2018), immune privilege and stem cell quiescence (manuscript in preparation with graduate student Joseph Palmer), and genetic background (Fialkokwski et al. 2019) in melanocyte stem cell maintenance ...

Though quiescence is a normal state for cells in many of our tissues, it can also be used by cancer cells to resist chemotherapy. A deeper understanding of this state could lead to better treatments ...

The primary focus of the Lacorazza lab is to study the molecular control of normal production of blood cells and malignant hematopoiesis. Our studies concentrate on two critical properties of HSCs: ...