Purpose: The clinical benefits, adverse effects, pharmacokinetics, and recommendations for the appropriate use of the aldosterone antagonists spironolactone and eplerenone in patients with heart ...

Eplerenone, a specific aldosterone receptor blocker with a lower incidence of the sex hormone-related side effects than spironolactone, has been used in several recent clinical trials in ...

Use of an aldosterone antagonist after myocardial infarction has improved outcomes in patients with heart failure with reduced ejection fraction, but whether it benefits others remains unclear.

investigated whether adding the aldosterone receptor antagonist spironolactone to renin–angiotensin system inhibition improved proteinuria in patients with diabetic nephropathy. Patients with ...

Key Takeaways Spironolactone is effective for both premenopausal and postmenopausal women Finasteride is primarily used for ...

Patients with recurrent ascites should receive a combination of an aldosterone antagonist (spironolactone, at a starting dose of 100–200 mg daily) plus furosemide (starting dose 40 mg daily).

Aldosterone antagonists (spironolactone, eplerenone) also known as “potassium sparing diuretics” block the action of aldosterone inhibiting the reuptake of sodium and water. Normally ...

Spironolactone – sometimes called “spiro” for short – has been a miracle drug for many suffering from acne, PCOS, and hair ...

Mineralocorticoid antagonists, or aldosterone antagonists (spironolactone, eplerenone) block the action of aldosterone, inhibiting the reuptake of sodium and water. Normally, when sodium is ...