"I work on a specific protein called SNAP-25," says Bhasne. "Without SNAP-25, the SNARE complex, which is responsible for guiding the synaptic vesicle to the right docking points on the ...

It does that by talking to the membrane fusion protein." More information: Chanwoo Lee et al, Exocyst stimulates multiple steps of exocytic SNARE complex assembly and vesicle fusion, Nature ...

Our group focuses on two assembly pathways: adaptor protein assembly during vesicle budding and SNARE complex assembly during vesicle fusion. We aim to use findings from these two model pathways to ...

n-Sec1 is the prototypic t-SNARE protector (Fig. 1). This mammalian homologue of the yeast protein Sec1 binds directly and tightly to the t-SNARE on the presynaptic plasma membrane, syntaxin-1A ...