Two ground-breaking papers, published back-to-back in Nature 54 years ago, independently showed that muscle shortens as a result of the sliding between the thick and thin filaments of the fibres ...

Striated muscle contraction requires intricate interactions of microstructures. The classic textbook assumption that myosin filaments are compressed at the meshed Z-disc during striated muscle fibre ...

As the world gears up for this summer's Olympics, scientists are celebrating the work of a British woman whose research contributed to a better understanding of how muscles function. It is the 50th ...

This is a preview. Log in through your library . Abstract Although it is generally believed that phosphorylation of the regulatory light chain of myosin is required before smooth muscle can develop ...

The sliding filament theory of muscle contraction has long provided a framework for understanding muscle biology and disease. In 1954, two teams showed that during shortening of striated muscle the ...