The thing you’re most likely to notice first is that the skin on your fingers, arms, legs, hands, feet, or face tightens, gets harder or thicker. Scleroderma symptoms may only affect small areas ...

Although scleroderma is rare ... As the disease progresses, the skin on the hands and feet undergoes significant changes, ...

Although scleroderma is a rare condition ... As the disease progresses, the skin on the hands and feet undergoes significant ...

Limited cutaneous scleroderma affects the skin slowly over time. It’s typically confined to your fingers, hands, lower arms and legs, usually below the knees. Diffuse cutaneous scleroderma takes ...

Peripheral artery disease. Lupus. Scleroderma. Raynaud’s syndrome is one of the most common causes of cold hands, according to the American Society for Surgery of the Hand.