In particular, they may have more symptoms relating to the skin or the lungs. Scleroderma means “hard skin.” Early symptoms of scleroderma include changes in the fingers and hands, such as ...

In some cases, it progresses slowly and is limited to the skin, while in others, it rapidly attacks internal organs such as ...

The physiology of scleroderma causing fibrosis is complex ... And some of the exact mechanisms that cause scarring in the lungs aren't quite clear, but there are some recognized predictors.

Scleroderma is classified as a rare, autoimmune, collagen-vascular disease of unknown etiology that can be difficult to diagnose and treat. Its onset can be insidious or rapid; the symptoms range ...

When her team looked at fluid from the lungs of scleroderma patients, endostatin was not at a level to help to reduce lung fibrosis. "For some reason, the levels of endostatin do not reach ...

Scleroderma interstitial lung disease (SLD ... overproduction of proinflammatory and profibrotic leukotrienes in the lungs of patients with SLD, and that leukotriene levels correlate with ...

A rare but serious lung problem is pulmonary hypertension, or high blood pressure in the blood vessels in the lungs. This condition is more common in people who have both lupus and another connective ...

Systemic sclerosis, or scleroderma, causes the hardening of skin and connective tissues. Often, the disease harms other organs, such as the heart, kidneys, lungs, and gastrointestinal tract ...

lungs, blood vessels, digestive system, and nerves. People with MCTD have symptoms of several diseases, including lupus, scleroderma, polymyositis or dermatomyositis, and rheumatoid arthritis.

Most people with scleroderma have autoantibodies. Several scleroderma-specific antibodies have been identified. These can help with diagnosis and give insight into the type of disease you may ...

Scleroderma is a chronic, often progressive, autoimmune disease where the immune system attacks the body. It can cause serious damage to internal organs like the lungs, heart, kidneys esophagus ...