Colossal uses gene editing to bring dire wolves back from extinction, marking a breakthrough in de-extinction science with the birth of Romulus and Remus.

The company’s innovative approach involves extracting DNA from ancient specimens, cloning it, and editing the genes to replicate the dire wolf's ancient traits. Romulus and remus: The new ...

Colossal's de-extinction process involved a sophisticated fusion of ancient DNA analysis, CRISPR gene editing, and ...

Time magazine announced that the biotechnology company Colossal has resurrected the dire wolf, a species that went extinct ...

rewrote the genetic code of the common gray wolf to match it, and, using domestic dogs as surrogate mothers, brought Romulus, Remus, and their sister, 2-month-old Khaleesi, into the world during ...

Three dire wolf pups — aptly named Romulus, Remus and Khaleesi — were successfully born using DNA from ancient dire wolf fossils and genes from their closest living relative, the gray wolf.

On April 8, Colossal announced it had used both cloning and gene-editing based on two ancient samples of dire wolf DNA to birth three pups, the six-month-old males Romulus and Remus and the two ...

While the wolves have stirred scientific debate, Colossal remains undeterred. The company says Khaleesi, Romulus, and Remus ...

Colossal Biosciences announced the birth of three dire wolf puppies. Romulus and Remus were born in October 2024, while Khaleesi arrived in January 2025. Dallas-based biotech company Colossal ...

On April 7, Colossal Biosciences announced the birth of three genetically-engineered pups named Romulus, Remus and Khaleesi. Colossal Biosciences is describing the dire wolf as the "world's first ...

Romulus and Remus were born in October 2024, and Khaleesi was born in January 2025. Photo Credit: X/@QuesaVerdadess Dire wolves were made famous by Game of Thrones, but now they're real again.