This important study provides evidence for dynamic coupling between translation initiation and elongation that can help maintain low ribosome density and translational homeostasis. The authors combine ...

Reconstructed 3D movie of ribosome moving through the elongation cycle visualized at different planes sectioning through the ribosome. Disclaimer: AAAS and EurekAlert! are not responsible for the ...

News Release 16-Jan-2025 Study captures high-resolution reconstructions of ribosome dynamics in situ Peer-Reviewed Publication Chinese Academy of Sciences Headquarters image: ...

The small subunit of the ribosome contains the mRNA binding channel, where the mRNA is threaded and positioned for decoding. The rRNA of the small subunit, particularly the 16S rRNA in prokaryotes and ...

These differences arise from structural elements in the human ribosome and in the human elongation factor, eEF1A, that together are responsible for faithfully incorporating the right tRNA for each ...

Andrew J. Adamczyk, Arieh Warshel, Converting structural information into an allosteric-energy-based picture for elongation factor Tu activation by the ribosome, Proceedings of the National Academy of ...

Ribosome biogenesis is a highly coordinated process that begins in the nucleolus and concludes in the cytoplasm, involving ribosomal RNA, ribosomal proteins, and biogenesis factors.