This prospective case-control study included 85 patients with lung involvement related to the COVID-19 virus and a group of ...

Advances in molecular genetics of retinal disease ... genes has highlighted the role of new biological pathways in retinal structure and function. The identification of the genes underlying ...

The sketch on the right shows the cell types and structure of the vertebrate retina in the same orientation as in the organoid: Here, light enters from below and traverses the entire retina until ...

Treatment with bioavailable small-molecule pharmacochaperones targeting the visual receptor rhodopsin offers a promising approach to prevent retinal ... and stabilize the structure of rhodopsin ...

Molecular simulations confirmed that ... HG9-91-01 exhibited neuroprotective effects by preserving retinal structure and preventing thinning—a common consequence of elevated IOP.

"This innovative approach could represent a turning point in recovery of sight in the field of degenerative retinal diseases." "Ziapin2 proves to be a key molecule in acting exclusively on the ...

Complex-conformation prediction using molecular dynamics simulation along ... In order to confirm that HG9-91-01 can protect the retinal structure in patients with AOH, the team plans on ...

In retinitis pigmentosa, the retina protein rhodopsin is often misfolded ... new drug-like molecules that bind to and stabilize the structure of rhodopsin to improve its folding and movement ...

Recently, we have been treated to structures of bacteriorhodopsin in ... domain appears to act as a ‘plug’ that may prevent the retinal from protruding from the protein upon isomerization ...