From this core mechanism Fc engineering has evolved over time into the "engine" of therapeutic antibody development. It ...

In a new study published in GEN’s sister peer-review journal, GEN Biotechnology, titled, “Exploring Structure-Function Relationships in Engineered Receptor Performance Using Computational Structure ...

Researchers have discovered how unstructured segments of surface proteins regulate the biological function of a cell. Their study, published in Nature Communications, sheds new light on the interplay ...

New research sheds light on the significance of the glucocorticoid receptor in drug-resistant prostate cancer, showing that the development of drug resistance could be prevented by limiting the ...

Details and references regarding individual diseases are provided in the Supplementary Appendix. CIDP denotes chronic inflammatory demyelinating polyneuropathy, Covid-19 coronavirus disease 2019, and ...

Psoriasis and psoriatic arthritis (PsA) are chronic, immune-mediated inflammatory diseases associated with several shared common comorbidities, of which obesity is one of the most prevalent. A complex ...

Laboratory research has shown that drugs such as semaglutide, already prescribed for type 2 diabetes and obesity, may shield ...

Researchers have synthesized enhanced vitamin K analogues that outperform natural vitamin K in promoting neuron growth. The new compounds, which combine vitamin K with retinoic acid, activate the ...

New research suggests that diabetes and weight-loss drugs known as GLP-1 receptor agonists may also help treat alcohol and ...

Which plant hormones are critical in responding to drought conditions? How do plant hormone responses adjust to environmental changes? An article published in the journal Trends in Plant Science ...