The Raf kinases, phosphatidylinositol-3-OH kinases and Ral-specific GEFs constitute three distinct classes of effector protein 2. Early studies focused on the part played by Ras in promoting cell ...

They have identified a crucial protein, G protein-coupled receptor 107 (GPR107), that plays a protective role in the kidneys of individuals with diabetic nephropathy (DN), a serious complication ...

G protein-coupled receptors (GPCRs) are integral membrane proteins with seven membrane-spanning helices. Upon binding to a ligand – which can range from small molecules like cyclic AMP to ...

Assessment of transfer entropy is useful for network analysis of cell signaling network providing information on the network topology and action points of genetic mutations and drug effect, thus will ...