Patients with secondary rectal cancer after radiotherapy for prostate cancer have shorter survival compared with matched treatment-naïve patients. However, a new study by investigators at MSK has ...

“Thus, for upper rectal cancer, the trade-off between using [neoadjuvant radiotherapy] to pursue better oncological outcomes and creating diverting stomas to lower the risk of symptomatic leak ...

The study included 323 patients with locally advanced rectal cancer (cancer that had grown outside the rectum but had not yet spread to other parts of the body) who were treated with either SCRT ...

Abstract no E25-837: “Preoperative Short-course Radiotherapy Followed by Chemotherapy and PD-1 Inhibitor for Locally Advanced Rectal Cancer: Phase II Results of STELLAR II”, presented in the ...

Umair Mahmood et al, Stratification to Neoadjuvant Radiotherapy in Rectal Cancer by Regimen and Transcriptional Signatures, Cancer Research Communications (2024). DOI: 10.1158/2767-9764.CRC-23-0502 ...

A new treatment for locally advanced rectal cancer shows favourable results in that surgery can sometimes be avoided completely. It also reduces the risk of recurrence. The method has been ...

Rectal cancer kills around 4,100 people in the UK (around 410 in Scotland) every year. Over the last 20 years, the incidence of early-onset rectal cancer has increased by 50.5% in the UK (53.6% in ...

Total neoadjuvant treatment using short-course radiotherapy and four CAPOX cycles in locally advanced rectal cancer with high-risk criteria for recurrence: a Swedish nationwide cohort study (LARCT ...

Reply to: Neoadjuvant Therapy for Locally Advanced Rectal Cancer: Omission of Radiotherapy or Not? The following represents disclosure information provided by authors of this manuscript. All ...

A new paradigm in rectal cancer treatment Together, these five studies demonstrate the transformative potential of radiotherapy as a curative and organ-preserving treatment.