The most common cause is LDH, which can lead to direct compression of the lumbar/sacral nerve root, reduced blood flow, and activation of inflammatory pathways. Acute radicular pain due to LDH ...

Epidural glucocorticoid injection is an intervention commonly used for managing lumbosacral radicular pain. The goal of the injection is to administer glucocorticoids to the epidural space to ...

The resulting imbalance in catabolic and anabolic responses leads to the degeneration of IVD tissues, as well as disc herniation and radicular pain. The release of chemokines from degenerating ...

Results indicate both injection types were effective for treating unilateral lumbosacral radicular pain (ULSRP). Two commonly delivered epidural injection modalities deliver minimal differences in ...

Men and women experience pain differently, and until now, scientists didn’t know why. New research says it may be in part due to differences in male and female nerve cells. Pain-sensing nerve ...

July 31, 2023 — Pain experts suggest that scrambler therapy, a noninvasive pain treatment, can yield significant relief for approximately 80% -- 90% of patients with chronic pain, and it may be ...

Most low-back pain with or without radicular pain or neurogenic claudication does not require immediate diagnostic imaging and can be managed in primary care. All patients with nonspecific low-back ...

The investigational injection SI-6603 may decrease pain scores for patients with radicular leg pain associated with lumbar disc herniation. Two phase 3 trials were performed in the U.S. and Japan.

The review updates a 2007 AAN assessment that reported epidural steroids may improve radicular lumbosacral pain between 2 and 6 weeks after the injection, but they did not improve function or ...

The global lumbosacral radicular pain management market is poised for significant growth, expected to achieve a market value of USD 0.9 billion in 2023 and forecasted to reach approximately USD 1.4 ...

“Clinically, the prescription of anticonvulsants for back and neck pain, including radicular pain in primary care, has increased by 535% in the last 10 years,” write the authors of this ...

Morphine is a powerful painkiller that belongs to the group of opioids. It blocks signals in the pain pathways and also ...