The general pattern that emerges in all these diseases is an abnormal tendency of proteins to aggregate as a result of misfolding. The aggregation can be caused by chance; by protein ...

Additional research is necessary to demonstrate definitively the involvement of protein misfolding and aggregation as a common cause of neurodegenerative diseases. Future work should also focus on ...

Misfolding of the prion protein triggers prion diseases such as Creutzfeldt-Jakob disease. All research findings to date indicate that the misfolded prion protein acquires toxic activity.

the scientists also uncovered new insights into the role of water around the protein surface that guides the misfolding process. A mutation commonly used to model tau-related diseases subtly ...

Researchers at Yale University show that latent infections in neurons may contribute to the development of Creutzfeldt-Jakob ...

Researchers developed trehalose-functionalized peptide amphiphiles (TPAs) that self-assemble into supramolecular ...

PROTEIN MISFOLDING DISEASES: Cambridge University Professor Christopher Dobson is due on campus next week to deliver a talk titled "Life on the Edge: The Nature and Origins of Protein Misfolding ...

the scientists also uncovered new insights into the role of water around the protein surface that guides the misfolding process. A mutation commonly used to model tau-related diseases subtly ...

Misfolding of the prion protein triggers prion diseases such as Creutzfeldt-Jakob disease. All research findings to date indicate that the misfolded prion protein acquires toxic activity.