The general pattern that emerges in all these diseases is an abnormal tendency of proteins to aggregate as a result of misfolding. The aggregation can be caused by chance; by protein ...

This is basic research, but it could eventually inform how we develop therapeutics for diseases linked to protein misfolding." In addition to Jiang, O'Brien and Fried, the research team includes ...

Dr. Joachimiak and his colleagues also plan to test whether further altering these monomers could make them useful for ...

While prion disorders like Creutzfeldt-Jakob disease are vanishingly rare in humans, studying these conditions could provide important insights into more common diseases that involve protein ...

This is basic research, but it could eventually inform how we develop therapeutics for diseases linked to protein misfolding." In addition to Jiang, O'Brien and Fried, the research team includes ...

2025--(BUSINESS WIRE)--Paradox Immunotherapeutics ("Paradox"), a pharmaceutical company focused on the development of innovative antibody therapies that treat protein misfolding diseases ...

With protein misfolding and aggregation prevalent in neurodegeneration, cancer, metabolic and ophthalmic diseases, the unmet clinical need presents huge opportunity to accelerate the discovery and ...

However, proteins can sometimes misfold, leading to the formation of aggregates or fibrils that are associated with various diseases, such as Alzheimer's, Parkinson's, and Huntington's. Studying the ...

Get Instant Summarized Text (Gist) A refined lab test for measuring protein aggregates in neurodegenerative diseases like Parkinson's has been developed, potentially enhancing diagnosis and drug ...

The general pattern that emerges in all these diseases is an abnormal tendency of proteins to aggregate as a result of misfolding. The aggregation can be caused by chance; by protein ...

This is basic research, but it could eventually inform how we develop therapeutics for diseases linked to protein misfolding.” In addition to Jiang, O’Brien and Fried, the research team ...