Additional research is necessary to demonstrate definitively the involvement of protein misfolding and aggregation as a common cause of neurodegenerative diseases. Future work should also focus on ...

Misfolding of the prion protein triggers prion diseases such as Creutzfeldt-Jakob disease. All research findings to date indicate that the misfolded prion protein acquires toxic activity.

the scientists also uncovered new insights into the role of water around the protein surface that guides the misfolding process. A mutation commonly used to model tau-related diseases subtly ...

Researchers at Yale University show that latent infections in neurons may contribute to the development of Creutzfeldt-Jakob ...

Researchers developed trehalose-functionalized peptide amphiphiles (TPAs) that self-assemble into supramolecular ...

A team of scientists has answered a long-standing question in cell biology, uncovering how the cell's main energy currency, ...

By developing investigational therapeutics targeting protein dysregulation in debilitating diseases such as Alzheimer’s and Parkinson's, the company has generated encouraging results from ...

the scientists also uncovered new insights into the role of water around the protein surface that guides the misfolding process. A mutation commonly used to model tau-related diseases subtly ...

Misfolding of the prion protein triggers prion diseases such as Creutzfeldt-Jakob disease. All research findings to date indicate that the misfolded prion protein acquires toxic activity.