The term “protease inhibitor” refers to a class of medications rather than to a single medication. Specifically, they are antiviral drugs. But unlike the many, more common antiviral drugs that ...

Protease inhibitors are one type of antiretroviral drug used to treat HIV. Their goal is to reduce the amount of HIV virus in the body to levels that are undetectable. That said, protease ...

A volume of 5 ml blood per sample was collected in a Vacutainer tube containing K 3 EDTA (Greimer Bio-one, Kremsmuenster, Germany) as anticoagulant and the protease inhibitor Trasylol (aprotinin ...

This is why these protease inhibitor drugs are ideally used in congregate living situations such as long-term care facilities, workplaces, schools, prisons, and family homes. Once an infection is ...

Over the seven years of the study, the percentage of samples with resistance to a protease inhibitor fell by half. A marked fall was also observed in the proportion of samples with resistance to drugs ...

Treatment with an antiretroviral regimen based on a protease inhibitor magnifies any underlying genetic susceptibility to diabetes for women living with HIV, investigators report in the online edition ...

some patients do not respond to protease inhibitor therapy. For most patients, the lack of response is not due to mutation of the HIV-1 protease. In this issue of the Journal of Clinical ...

This drug, currently known as PF-07321332, is a protease inhibitor "designed to block the activity of the main protease enzyme that the coronavirus needs to replicate." This drug is not a ...

Simnotrelvir is an oral 3-chymotrypsin–like protease inhibitor that has been found to have in vitro activity against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and potential ...

The oral protease inhibitor nirmatrelvir has shown substantial efficacy in high-risk, unvaccinated patients infected with the B.1.617.2 (delta) variant of severe acute respiratory syndrome ...