Half the cells were lysed in 20 mM Tris-HCl pH 7.4, 150 mM NaCl, 0.2% NP-40 containing protease inhibitors and centrifuged. Lysates were analyzed for caspase-8 (MBL), caspase-9, caspase-3 ...
These proteases typically lie dormant in the healthy ... Initiator caspases (such as caspase 8 and caspase 9) activate the effector caspases and have long prodomains that allow them to interact ...
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