According to Gentile, the cell line routinely achieves yields exceeding 4×10¹⁴ vector genomes per liter (vg/L) across a range of serotypes, which are levels comparable to leading commercial ...

Human embryonic kidney (HEK293) cells are the most commonly used cell line to produce viral vectors for gene therapy. Due to the complexity of their production and purification, viral vectors can be ...

Early work on continuous, high-titre vector production established efficient systems for the stable expression of essential viral proteins, thereby setting benchmarks for yield and reproducibility ...

Furthermore, AI is making manufacturing more efficient by optimizing production schedules by analyzing data, including order volumes, machine availability, and workforce capacity.

Shutdowns, scheduled or not, can eat up to 1%-10% of available production time. These nonproductive hours can’t be recovered but you still have to bear the costs.

Robots have been working in car factories for decades now, starting with machines performing some welds on a General Motors production line back in 1961. Now, robots work alongside people on ...