The National Prion Disease Pathology Surveillance Center (NPDPSC) is the only Center of its kind in the U.S., which coordinates autopsies and neuropathologic examinations of suspected prion disease ...

The prion hypothesis remains controversial even ... its own misfolding to trigger the formation of proteinaceous plaques and neurological disease runs athwart much of the conventional wisdom ...

A recent paper reported the in vitro generation of new prion strains, supporting the idea that 'strain-ness' is encoded in the protein structure itself. This lays the groundwork for a ...