“Previously Alzheimer’s research has been stuck looking at collateral damage in the form of misfolded, dead proteins that form plaques and tangles. Now it turns out that it is prion activity that ...

Sponsor Message Strittmatter says there's no evidence the prion proteins fold into an abnormal shape or actually cause Alzheimer's. Instead, they seem to interact with early stage plaques in the ...

Neuropathological examination during end-stage disease showed the deposition of prion protein in the form of frequent cortical amyloid plaques, cerebral amyloid angiopathy, and tauopathy.

While there have been extensive studies of these plaques and tangles in the brains of people with Alzheimer’s, it can be challenging to discern which changes in the brain are from old age and which ...

When prion proteins begin to fold abnormally and clump together — called amyloid plaques — it leads to brain damage. Disease-causing prions can transmit in various ways, for example ...

Mark Zabel: Prion diseases belong to a larger family of diseases that we refer to as protein misfolding diseases. These are diseases that also are caused by normal proteins that we all express that ...

Scientists at Northwestern University and University of California, Santa Barbara have created the first synthetic fragment of tau protein that acts like a prion. The "mini prion" folds and stacks ...

Prion diseases are rare, fatal neurodegenerative disorders caused by misfolded prion proteins (PrP) in the brain. This can lead to memory loss, behavior changes, and movement problems. Prion ...

When Sonia Vallabh learned she has the genetic mutation for prion disease, she and her husband dropped everything to change careers. Today, they lead a Harvard/MIT lab searching for a cure.

"Previously Alzheimer's research has been stuck looking at collateral damage in the form of misfolded, dead proteins that form plaques and tangles. Now it turns out that it is prion activity that ...

While there have been extensive studies of these plaques and tangles in the brains of people with Alzheimer’s, it can be challenging to discern which changes in the brain are from old age and which ...