You don't have to go to the doctor for this prescription-strength formula that reviewers say works faster than all others.

However, according to Dr. Ariel Ostad, a cosmetic surgeon based in New York City, products that use a prescription-strength retinoid called adapalene are outliers in this pricey OTC mark-up.

I really don’t have to wear any makeup now." — Amazon customer $36 at Amazon Differin contains 0.1% adapalene, a type of retinoid that was previously only available by prescription.

I really don’t have to wear any makeup now." — Amazon customer $36 at Amazon Differin contains 0.1% adapalene, a type of retinoid that was previously only available by prescription.

Musely, a telehealth-based prescription skin-care brand, is here with a solution— Musely FaceRX The Eye Serum ($74). It’s an eye serum that blends a super-low concentration of tretinoin with a ...

For decades, finding the best tretinoin cream was, in theory, simple enough: Schedule an appointment with your dermatologist for a prescription. But with time and energy at a premium these days ...

While prescription-strength retinoids are more effective, over-the-counter ones work well, too. There are plenty of affordable options under $30 from brands like The Ordinary, RoC, and CeraVe.