Phosphorylation can either activate a protein (orange) or inactivate it (green). Kinase is an enzyme that phosphorylates proteins. Phosphatase is an enzyme that dephosphorylates proteins ...

(A) Illustrates the general model. Protein1 is phosphorylated by kinase1, and is subsequently recognized by protein 2 which contains the phosphopeptide binding domain. The assembly or disassembly ...

TFE3 fusion proteins are the oncogenic drivers of translocation renal cell carcinoma but their mechanism of action remains ...