The field of pharmacophore modeling has steadily emerged as a cornerstone in the rational design of kinase inhibitors. By abstracting the essential molecular features required for optimal binding to ...

Even though AI-designed drugs aren’t yet a household term for FDA-approved, commercially available therapies, they are a reality in clinical development pipelines. In spring 2024, CBER reported more ...

At the heart of every biological process, from the replication of cells to the functioning of the human brain, lies the intricate world of proteins. Understanding the structure of these molecules, ...

Innovative technologies such as artificial intelligence (AI), machine learning, and quantum computing can accelerate the design and discovery of novel drugs to fight cancer. A new peer-reviewed study ...

Bacterial infections are common and can impact various organs and tissues in the human body.² Clinicians typically prescribe antibiotics to treat these infections; however, many bacteria have ...

Proteins are life's molecular workhorses, doing everything from turning sunlight into food to fighting viruses. They are built from 20 different types of amino acid molecules, so even a small protein ...