Pro-905, a Novel Purine Antimetabolite, Combines with Glutamine Amidotransferase Inhibition to Suppress Growth of Malignant Peripheral Nerve Sheath Tumor. Molecular Cancer Therapeutics, 2023; 22 ...

A combination of two cancer drugs could be effective against malignant peripheral nerve sheath tumors (MPNSTs) - soft tissue tumors that are stubbornly resistant to chemotherapy and radiation ...

Cortes-Ciriano, I., et al. (2023) Genomic patterns of malignant peripheral nerve sheath tumor (MPNST) evolution correlate with clinical outcome and are detectable in cell-free DNA. Cancer ...

The focus of this month’s blog post is a discussion of malignant peripheral nerve sheath tumors (MPNSTs), which represent one of the few potentially life-threatening complications of neurofibromatosis ...

Researchers from Johns Hopkins University and affiliated organizations have published details on the discovery and preclinical characterization of a purine antimetabolite, Pro-905, which is being ...

Next, I’d like to address the issue of atypical neurofibromas and their potential to become malignant peripheral nerve sheath tumors (MPNST), probably the most feared complication of NF1. Occurring in ...

Peripheral neuropathy is nerve damage usually found in your hands or feet. If you have it, these areas might feel numb, tingly, or weak. It might feel like “pins and needles.” ...

Peripheral nerve sheath tumors (PNSTs), particularly schwannomas, are the most common type of nerve tumors. These tumors arise from the protective sheath surrounding peripheral nerves and can ...

Among the peripheral nerve sheath tumors (PNSTs) evaluated, which included 20 MPNSTs and two neurofibromas, only 9% showed reactivity for pan-cytokeratin, 18% for CK7, and none for CK19. [These ...

Background: Malignant peripheral nerve sheath tumors (MPNST) constitute a group of malignant tumors that arise from schwann cells of the peripheral nerve sheath. Neurofibromatosis type 1 (NF1), an ...

Bin Liu, Wang Xin, Jian-Rong Tan, Rui-Ping Zhu, Ting Li, Dan Wang, Sha-Sha Kan, Ding-Kui Xiong, Huan-Huan Li, Meng-Meng Zhang, Huan-Huan Sun, William Wagstaff, Chan Zhou, Zhi-Jian Wang, Yao-Guang ...

August 06, 2012 Pathologic Complete Response of a Malignant Peripheral Nerve Sheath Tumor in the Lung Treated With Neoadjuvant Ifosfamide and Radiation Therapy Authors: Kyle C. Cuneo, Richard F.