Most patients had previously been treated with penicillin or one of the sulfonamides and had failed to make a satisfactory clinical response. In most cases streptomycin was administered ...

In penicillin-sensitive alpha and non-hemolytic streptococcal endocarditis (penicillin MIC0.1 mcg/mL), streptomycin may be used for 2-week treatment concomitantly with penicillin. The streptomycin ...

The mass manufacture of penicillin during World War II stimulated urgent interest ... Seen here in Waksman's notes are his April 1943 experiments with nutrient formulas for growing ...

This was significant since penicillin had no effect on gram-negative bacteria. Even more exciting to the researchers was that streptomycin exhibited activity in vitro activity against Mycobacterium ...

PENICILLIN and streptomycin have been commonly added to growth media used in the culture of human leucocytes for cytogenetic analysis. Since the literature on human cytogenetics is increasing ...

The key that unlocked streptomycin was Schatz's success in ... virulent strains of bacteria that had proven resistant to penicillin, itself a new wonder drug. Years later, Schatz described the ...

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Cultivating penicillin proved difficult and the small quantities that ... first applying its fermentation techniques to the manufacture of streptomycin, a drug developed by Selman Waksman and his ...

Alexander Fleming’s 1928 discovery of a mold with antibacterial properties was only the first serendipitous event on the long road to penicillin as a life-saving drug. Hannah is an Assistant Editor at ...