St. Jude announces $13 million investment to expand the understanding of G-protein coupled receptors. Download PDF Copy; Reviewed. St. Jude Children's Research Hospital Jan 18 2024.

Allosteric modulation of G protein-coupled receptors as a novel therapeutic strategy in neuropathic pain. Compuscript Ltd. DOI 10.1016/j.apsb.2023.07.020 ...

19 F NMR revealed several functional activation states of A 2A R when it is coupled to G s and G o G-proteins. When A 2A R is engages with its preferred G s partner, the receptor adapts long-lived ...

MCARH109 is a first-in-class G protein–coupled receptor, class C, group 5, member D (GPRC5D)-targeted chimeric antigen receptor (CAR) T-cell therapy for patients with relapsed/refractory multiple ...

G protein–coupled receptor, class C group 5 member D (GPRC5D), a type C 7-pass transmembrane receptor protein, is expressed on malignant and normal plasma cells at least 500-fold higher in bone marrow ...

Although G protein-coupled receptors (GPCRs) are crucial to the regulation of most functions in the human body, very little is known about how they work. In a new study, researchers at the Biozentrum ...

Understanding what drives progression may help identify proteins and pathways that can be targeted to slow down the disease. Hepatocellular carcinoma (HCC), which accounts for up to 80% of cases of ...

A recent study published in Nature by a research team from the United States and China introduced a new class of engineered G-protein-coupled receptors (GPCRs) called programmable antigen-gated ...