[1] COPD has a very complex pathogenesis, in which the typically occurring airflow limitation is only the final consequence of a cascade of events that start much earlier than the appearance of ...

Over the past years, many details of the molecular pathogenesis of COPD have been revealed. This has offered new points of possible interventions, many of which are currently under investigation.

Smoking is associated with chronic obstructive pulmonary disease (COPD) and plays an important role in the pathogenesis and progression of neurodegenerative diseases. Together, these diseases pose ...

Scheibye-Knudsen: Lung inflammation is thought to be part of the pathogenesis of COPD, and IL-8 is one of the inflammatory cytokines that may contribute to reduced lung function over time.

In conclusion, Tim-3 was characterized as a novel immune checkpoint molecule with pathophysiological significance in respiratory oncology. Its stage-dependent expression dynamics and multimodal ...