Patagonia-Sonoita Scenic Road. Pastoral grasslands, vineyards and hidden lakes are among the last things people expect to find in southern Arizona, just miles from the Mexican border.

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Details: 3969 AZ-82, Sonoita. 520-338-8823 www.runewines.com. Callaghan Vineyards It has been making waves since the mid-1990s, and its wines have been served at the White House four times.