There is currently no effective treatment, but new research suggests promise for exosomes, tiny sacs released by cells. Non-parenchymal cells like hepatic stellate cells (HSCs), Kupffer cells (KCs ...

The major interest is in the endothelial cell secretome and the crosstalk between endothelial and parenchymal cells, and how this is changed in different diseases. The ultimate goal is to identify ...

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Despite being mainly composed of terminally differentiated myocytes that cannot re-enter the cell cycle, the heart is not a postmitotic organ and maintains some capacity to form new parenchymal ...

Stationed within the meninges, squads of immune cells lie in wait, ready to unleash an inflammatory assault within the brain if needed. Holding these trigger-happy troops back during peacetime falls ...

Lineage Cell Therapeutics (LCTX) announced that the Company has initiated the DOSED clinical study. The DOSED study will evaluate the safety ...

Mice with liver parenchymal cell (LPC)-specific ablation of NEMO develop spontaneous steatohepatitis and hepatocellular carcinoma. Disease pathogenesis in this model requires FADD (FAS-associated ...

Moreover, the cells and soluble factors participating in this response in liver are also similar to those in parenchymal injury to kidney, lung, or skin. Fibrosis occurs earliest in regions where ...

Lineage Cell Therapeutics initiates DOSED clinical study of OPC1 for spinal cord injury: Carlsbad, California Thursday, February 13, 2025, 14:00 Hrs [IST] Lineage Cell Therapeutic ...