If optic nerve hypoplasia is suspected in a child, the utmost priority should be given to evaluation of pituitary hormone levels, given the potentially life-threatening consequences, especially if ...

Optic nerve hypoplasia may present as a unilateral or bilateral disorder. Fundus examination may reveal a double-ring sign, vascular tortuosity, optic nerve pallor, or an enlarged cup.

Reference Dahl S, Pettersson M, Eisfeldt J, et al. Whole genome sequencing unveils genetic heterogeneity in optic nerve hypoplasia. PLoS One. 2020;15 (2):e0228622. doi: 10.1371/journal.pone.0228622.

Like Daegan, 6-year-old Rylea was born with optic-nerve hypoplasia. Because her optic nerves did not develop normally during pregnancy, she was blind and could not detect light. Like Daegan, Rylea ...

Optic nerve hypoplasia accounts for about 15 percent to 25 percent of infants with serious vision loss, according to the NIH, and although precise numbers are unavailable, the incidence of the ...

They would not send light back to the brain. People with optic-nerve hypoplasia never develop vision. This is the first case ever -- since the Bible -- where someone's sight has been restored.

Optic nerve hypoplasia (ONH) is known to be associated with hypothalamic-pituitary dysfunction including growth hormone deficiency (hGH-D), panhypopituitarism and diabetes insipidus (DI). Previous ...

Ziva has been blind since birth and has optic nerve hypoplasia, a condition where the optic nerves that connect the eyes to the brain are underdeveloped. Ziva can see some lights, colors and shapes, ...