Researchers primarily evaluated patients’ responses via the Bowel Function Index (BFI), which they described as a three-item subjective scale developed for opioid-induced constipation, where patients ...

Opioid-induced constipation is defined as a reduction in bowel frequency (less than 3 bowel movements per week in clinical studies), development of straining to pass bowel movements, a sense of ...

Before screening, patients had been receiving palliative opioid therapy and had opioid-induced constipation. They were on a stable opioid regimen for at least three days before randomization.

May 12, 2009 (San Diego, California) — Constipation is a well-known adverse effect of opioid analgesics but often goes undiagnosed because patients can be reluctant to talk about it, experts ...

Conventional approaches to treatment of opioid-induced constipation (OIC) include the use of treatment modalities that address non-opioid-related constipation as well as several relatively new ...

The FDA has approved the oral treatment for opioid-induced constipation naloxegol (Movantik), according to a Gastroenterology & Endoscopy News report. Movantik is designed for adults with chronic ...

The Food and Drug Administration recently approved the tablet form of Relistor to treat opioid-induced constipation. Relistor, produced by Tarrytown, N.Y.-based Progenics Pharmaceuticals, was ...

Naldemedine for opioid-induced constipation in patients with cancer: A multicenter, double-blind, randomized, placebo-controlled trial. Journal: Journal of Clinical Oncology. DOI: 10.1200/JCO.24.00381 ...

Naldemedine for Opioid-Induced Constipation in Patients With Cancer: A Multicenter, Double-Blind, Randomized, Placebo-Controlled Trial The article by Hamano et al entitled “Naldemedine for ...

Evidence-based recommendations on naloxegol (Moventig) for treating opioid-induced constipation in adults.. Last reviewed: 9 July 2018. We checked this guidance and found nothing new that affects the ...

Research Reveals Reduction in Hospitalization Rates, Length of Stay and Health Care Costs When Treating OIC with FDA-Approved Prescription Medications LAVAL, QC, March 24, 2022 /PRNewswire ...

Publisher’s Note. The article by Hamano et al entitled “Naldemedine for Opioid-Induced Constipation in Patients With Cancer: A Multicenter, Double-Blind, Randomized, Placebo-Controlled Trial” (Journal ...