The search for Northwest Orient Flight 2501 has been called off after a 20-year search. The passenger plane carrying 58 people disappeared over Lake Michigan on June 23, 1950 and no victims were ...

Northwest Orient Flight 2501, a four-engine propeller-driven DC-4, left New York's LaGuardia Airport the evening of June 23 bound for Seattle with planned stops in Minneapolis and Spokane, Wash.

Northwest Orient Flight 2501 that disappeared over Lake Michigan in 1950. NEED TO KNOW. A 20-year search for a flight that disappeared over Lake Michigan in 1950 has been called off.

Northwest Orient Airlines Flight 2501, at the time the deadliest commercial airlines disaster in American history, disappeared when it flew into a storm over Lake Michigan on June 24, 1950.

In 1950, Northwest Orient Flight 25-01 vanished over Lake Michigan during severe weather, resulting in the deaths of all 58 people on board. Despite extensive searches, the wreckage was never found.

From Seat 18C on the Northwest Orient flight, he told a flight attendant he had a bomb. If they gave him $200,000 – the equivalent of about $15,500,000 today – he would free the 36 passengers.

The hijacker, dubbed "D.B. Cooper," has remained a mystery in the 40 years since he jumped from a Northwest Orient Airlines 727 flight with $200,000 in ransom.

It adopted the name “Northwest Orient” for advertising purposes. The airline’s Asian connections proved useful in 1950 when the U.S. government chose the airline for the Korean Air Lift mission.