Further, the role of the normal prion protein known as PrPc in iron metabolism may provide a target for strategies to maintain iron balance and reduce iron-induced neurotoxicity in patients ...

A new study suggests that the normal form of prion protein helps maintain the insulation that speeds electrical signals along nerve fibers. In its twisted Mr. Hyde form, the prion protein causes ...

In the study, the researchers created a large fragment of the normal prion protein -- a harmless protein found in all mammals examined. They then folded this fragment into the abnormal shape that ...

After silently lurking for almost 50 years, a prion disease erupted in the brain of a woman in the US, triggering a rapid and ...

As part of the new study, Prusiner, Legname and their colleagues created a large fragment of a normal prion protein and folded it using lab techniques into an abnormal shape, which they suspected ...

Misfolded, prion-like proteins drive the progression ... which ultimately damage brain health but are difficult to diagnose. When a normal protein encounters the pathological tau fibrils, the ...

Santa Barbara have created the first synthetic fragment of tau protein that acts like a prion. The “mini prion” folds and stacks into strands (or fibrils) of misfolded tau proteins, which then ...

Further, the role of the normal prion protein known as PrPc in iron metabolism may provide a target for strategies to maintain iron balance and reduce iron-induced neurotoxicity in patients ...

In the study, the researchers created a large fragment of the normal prion protein -- a harmless protein found in all mammals examined. They then folded this fragment into the abnormal shape that ...

Misfolded, prion-like proteins drive the progression ... which ultimately damage brain health but are difficult to diagnose. When a normal protein encounters the pathological tau fibrils, the ...