Nitrofurantoin is an antibiotic that fights bacteria. It is used to treat and prevent uncomplicated urinary tract infections. It works by killing the bacteria that cause such disease. But ...

In both studies, people were randomly assigned to take either Blujepa twice a day for five days or another antibiotic, nitrofurantoin (Macrobid), twice a day for five days. Nitrofurantoin is ...

Approximately 200 cases of pulmonary sensitivity reaction to nitrofurantoin have been reported since 1959. The acute reaction commonly begins with fever, cough and dyspnea; eosinophilia or skin ...

GSK tested the antibiotic in the phase 3 Eagle-2 and Eagle-3 trials, pitting its twice-daily option against longtime standard-of-care nitrofurantoin for five days. Pfizer, Gilead and GSK to seize ...

Please provide your email address to receive an email when new articles are posted on . Nitrofurantoin decreased episodes by 79%, and cranberry juice and tablets reduced episodes by 59% compared ...

Phase 3 trials showed gepotidacin's non-inferiority to nitrofurantoin, with superior results in one trial. The most common adverse event was mild to moderate diarrhea, with no life-threatening ...

The urinary recovery of nitrofurantoin after a single 100-mg oral dose was studied in subjects with varying renal function. Almost all uremic patients excreted little or no drug in the urine ...

Results of two phase III trials -- EAGLE-2 and EAGLE-3-- supported approval, demonstrating that the first-in-class antibiotic was noninferior to nitrofurantoin, a standard option for uncomplicated ...

Study participants were randomly assigned to receive gepotidacin 1500mg twice daily or nitrofurantoin 100mg twice daily for 5 days. The primary endpoint for both trials was the combined clinical ...

Urinary tract infections (UTIs) are among the most common medical issues women experience; up to 60% of women will get one during their lifetime. Older, post-menopausal women are especially ...

Announcing a new article publication for BIO Integration journal. Nitrofurantoin is a BCS II drug with a low solubility and dissolution rate. Therefore, the pharmaceutical applications of ...