Katyal N, Govindarajan R, Goyal N, et al. Ravulizumab use for acetylcholine receptor-positive generalized myasthenia gravis in clinical practice. Front Neurol . 2024;15:1378080. doi:10.3389/fneur ...

Placebo-controlled trials indicate that cytisine, a partial agonist that binds the nicotinic acetylcholine receptor and is used ... patches (in doses of 7 mg, 14 mg, or 21 mg) and for gum (2 ...

Based on the composition of the five subunits forming functional neuronal nicotinic acetylcholine receptors ... Although the intracellular mechanism that mediate the modulation of neuronal ...

Studies found specific nicotinic acetylcholine receptors activated ... pathway in the brain that mediates the nicotine-triggered mechanism by which cigarette smoking suppresses appetite.

The α7 nicotinic acetylcholine receptor (α7nAChR) binds the amyloid-β peptide ... The paper does not settle the question of mechanism, but one possibility is decreased internalization of Aβ (Nagele et ...

It was inferred that incubation at 37°C for 24 hours was sufficient to detect the binding of the peptides to the human nicotinic acetylcholine receptor (a7-AChR). Additionally, a7-AChR also bound ...

In AD therapy, it may be time for an alternative target to shine: the α7 nicotinic acetylcholine ... the α7 receptor in the hippocampus and prefrontal cortex. When the Aβ-infused animals were injected ...

Autoantibodies specific for nicotinic acetylcholine receptors ... mutant mice lacking the α3 subunit of the ganglionic acetylcholine receptor. 26 Because the various forms of acquired ...

today announced an update on the company’s α7 Nicotinic Acetylcholine Receptor (nAChR) Positive Allosteric Modulator (PAM) collaboration with MSD (known as Merck & Co., Inc., Rahway NJ ...

The goal of this prospective study was to evaluate the association among orthostatic hypotension, nicotinic acetylcholine receptor autoantibody titers, and cognitive impairment in patients with AAG.