Systemic sclerosis is, as the name defines, a thickening of the tissues in the skin. And it's also involving multiple organs in the body, not just the skin. And one of these is the lungs, so there ...

Systemic sclerosis (SSc) is a rare autoimmune disease that can harden the skin, impair blood flow, and damage internal organs such as the lungs and kidneys. But no two patients experience the ...

A Case of Nephrogenic Fibrosing Dermopathy/Nephrogenic Systemic Fibrosis Andrew S. Weiss; M. Scott Lucia; Isaac Teitelbaum Disclosures Nat Clin Pract Nephrol. 2007;3 (2):111-115. 0 ...

Systemic sclerosis (SSc), or scleroderma, is a chronic autoimmune condition characterized by the overproduction of collagen, a protein that gives tissues strength and structure.

The Food and Drug Administration (FDA) has granted EYD-001, a selective transforming growth factor-β-activated kinase 1 (TAK1) inhibitor, Orphan Drug designation for the treatment of systemic ...

Key takeaways: Nearly 10% of patients with systemic sclerosis had systemic sclerosis sine scleroderma, a subtype without skin fibrosis. The patients had a higher prevalence of interstitial lung ...

In addition to these symptoms, systemic sclerosis can affect internal organs, such as the lungs and kidneys, with serious consequences. We know that immune dysregulation causes vascular damage and ...

Gunnarsson K, et al. Hematological malignancies in systemic sclerosis, a population-based nationwide register study. Presented at EULAR 2025; OP0221. DOI: 10.1136/annrheumdis-2025-eular.B444.

Although less common than other subtypes of systemic sclerosis (SSc), systemic sclerosis sine scleroderma (ssSSc) makes up more than 8% of SSc cases and "should not be neglected," according to a ...

In patients with systemic sclerosis, clinical response was assessed by means of the score on the European Scleroderma Trials and Research Group (EUSTAR) activity index (range, 0 to 10, with higher ...