“The strategy is now investigated in rectal cancer for tailored management according to response to induction modified FOLFIRINOX.” A move toward total neoadjuvant therapy in rectal cancer has ...

“The trade-off between [neoadjuvant radiotherapy] use and diverting stoma nonreversal may not be justified for upper rectal cancer, emphasizing the importance of considering tumor height when ...

Study: Total neoadjuvant treatment using short ... The RAPIDO (short for Rectal Cancer and Preoperative Induction Therapy Followed by Dedicated Operation) trial compared CRT with a TNT regimen ...

Ding and colleagues conducted a retrospective analysis to evaluate the feasibility and efficacy of neoadjuvant anti-PD-1 therapy for patients with localized dMMR/MSI-H colorectal cancer.

Key recommendations include the following: Neoadjuvant radiation therapy is recommended for patients with stage II or III rectal cancer to reduce their risk of locoregional recurrence. A thorough ...

Patients with localized rectal cancer classified as low risk can ... of nCRT in low-risk patients and escalation of neoadjuvant therapy in high-risk patients to improve long-term outcomes ...

guidelines for locally advanced rectal cancer treatment endorse watch-and-wait for patients with clinical complete response after neoadjuvant therapy,” said Zhao. “Our protocols follow established ...

Chemotherapy and radiotherapy may be efficacious enough for certain patients with advanced rectal cancer ... according to the American Cancer Society. For cancers that may not be able to be completely ...