Ryan Alto, a 48-year-old from California, developed what seemed like a routine flu. He had a headache, body aches, and ...

A California man was diagnosed with Anti-NMDA receptor encephalitis, a rare autoimmune brain disorder often mistaken for ...

The team analyzed samples from human postmortem brains, including healthy individuals and patients at various stages of neurodegeneration. The results show a distinct distribution of NMDA ...

The development saga for the depression molecule has been rocky for years, unable to ease symptoms in multiple late-stage ...

Many individuals diagnosed with anti-NMDA receptor encephalitis continued to have cognitive issues — particularly with memory and language — up to 3 years after diagnosis, according to a ...

Figure 2. Demonstration of N-methyl-D-aspartate receptor antibodies in the patient's cerebrospinal fluid.(A,B) Sagittal section of rat hippocampus incubated with the patient's cerebrospinal fluid ...

Scientists at Shanghai Tech University have used the scaffold-hopping artificial intelligence model Geminimol to identify N-methyl-D-aspartate (NMDA) receptor ligands that show selectivity and ...

NMDA receptor inhibitors, like MK-801 and memantine, lead to weight reduction in rats and reduced palatable food choices in rodents and non-human primates.

Neumora Therapeutics reports NMDA receptor positive allosteric modulators. Feb. 14, 2025. Neumora Therapeutics Inc. has patented NMDA receptor positive allosteric modulators reported to be useful for ...

Single injection of ketamine no longer causes antidepressant effects on day 3 or day 7. Credit: Nature (2023). DOI: 10.1038/s41586-023-06624-1 ...